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XIGDUO XR Side Effects

What you should know

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XIGDUO XR Side Effects

What you should know

When taking any medication, it’s important to understand the benefits, as well as the risks

XIGDUO (zig-DOO-oh) XR may cause serious side effects, including lactic acidosis. Metformin, one of the medicines in XIGDUO XR, can cause a rare, but serious, side effect called lactic acidosis (a build-up of lactic acid in the blood) that can cause death. Lactic acidosis is a medical emergency and must be treated in a hospital.

Stop taking XIGDUO XR and call your healthcare provider right away if you have any of the following symptoms which could be signs of lactic acidosis:

  • you feel cold in your hands or feet
  • you feel very weak or tired
  • you have unusual (not normal) muscle pain
  • you have trouble breathing
  • you have unusual sleepiness or sleep longer than usual
  • you have stomach pains, nausea, or vomiting
  • you feel dizzy or lightheaded
  • you have a slow or irregular heartbeat

You have a higher chance of getting lactic acidosis with XIGDUO XR if you:

  • have severe kidney problems
  • have kidneys that are affected by certain x-ray tests that use injectable dye
  • have liver problems
  • drink alcohol very often or drink a lot of alcohol in short-term “binge” drinking
  • get dehydrated (lose a large amount of body fluids). This can happen if you are sick with a fever, vomiting, or diarrhea. Dehydration can also happen when you sweat a lot with activity or exercise and do not drink enough fluids
  • have surgery
  • have a heart attack, severe infection, or stroke

There are other serious side effects associated with XIGDUO XR. Click on the links below to learn more about each one listed.

The most common side effects of XIGDUO XR include:

  • vaginal yeast infections and yeast infections of the penis
  • stuffy or runny nose and sore throat
  • diarrhea
  • headache
  • nausea
  • vomiting

Tell your healthcare provider or pharmacist if you have any side effect that bothers you or does not go away.

These are not all of the possible side effects of XIGDUO XR. For more information, ask your healthcare provider or pharmacist.

Call your healthcare provider for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

 
Check out an offer for most patients to get XIGDUO XR for a $0* co-pay
*Eligible commercially insured patients can get XIGDUO XR for as low as $0 as long as their doctor prescribes it. Subject to eligibility and monthly savings limit. Restrictions apply. Not available for government-insured patients.